NKTR (Nektar Therapeutics) ROE % Adjusted to Book Value: -14.65% (As of Mar. 2026)


NKTR Nektar Therapeutics NKTR
42 GF Score
Price $65.14
GF Value $6.01
Valuation Significantly Overvalued
! 5 Warning Signs
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What is Nektar Therapeutics ROE % Adjusted to Book Value?

Nektar Therapeutics NKTR -2.31% 42 ROE % Adjusted to Book Value is -14.65% as of Mar. 2026. GuruFocus rates NKTR with a GF Score™ of 42/100 and a GF Value™ of $6.01 (Significantly Overvalued). The stock has 5 warning signs investors should review.

Nektar Therapeutics's ROE % for the quarter that ended in Mar. 2026 was -53.93%. Nektar Therapeutics's PB Ratio for the quarter that ended in Mar. 2026 was 3.68. Nektar Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 was -14.65%.


Nektar Therapeutics ROE % Adjusted to Book Value Related Terms


Nektar Therapeutics ROE % Adjusted to Book Value Historical Data

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The historical data trend for Nektar Therapeutics's ROE % Adjusted to Book Value can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Nektar Therapeutics ROE % Adjusted to Book Value Chart

Nektar Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
ROE % Adjusted to Book Value
Get a 7-Day Free Trial Premium Member Only Premium Member Only -16.16 -60.68 -133.67 -43.70 -22.73

Nektar Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
ROE % Adjusted to Book Value Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -59.35 0.00 -35.53 -17.21 -14.65

NKTR vs PHVS, KOD, RARE: ROE % Adjusted to Book Value Comparison

For the Biotechnology subindustry, Nektar Therapeutics's ROE % Adjusted to Book Value, along with its competitors' market caps and ROE % Adjusted to Book Value data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Nektar Therapeutics ROE % Adjusted to Book Value vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Nektar Therapeutics's ROE % Adjusted to Book Value distribution charts can be found below:

* The bar in red indicates where Nektar Therapeutics's ROE % Adjusted to Book Value falls into.


NKTR
42GF Score
Nektar Therapeutics NKTR
ROE % Adjusted to Book Value is just one metric. See GF Score™, valuation, warning signs, and more.
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Nektar Therapeutics ROE % Adjusted to Book Value Calculation

Nektar Therapeutics's ROE % Adjusted to Book Value for the fiscal year that ended in Dec. 2025 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-217.94% / 9.59
=-22.73%

Nektar Therapeutics's ROE % Adjusted to Book Value for the quarter that ended in Mar. 2026 is calculated as

ROE % Adjusted to Book Value=ROE % / PB Ratio
=-53.93% / 3.68
=-14.65%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a ROE % Adjusted to Book Value of -14.65% mean?
Nektar Therapeutics (NKTR) has a ROE % Adjusted to Book Value of -14.65% as of Mar. 2026. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Nektar Therapeutics and its competitors.
Is Nektar Therapeutics' ROE % Adjusted to Book Value too high?
Nektar Therapeutics' current ROE % Adjusted to Book Value is -14.65%. Overall, Nektar Therapeutics has a GF Score™ of 42/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Nektar Therapeutics' ROE % Adjusted to Book Value compare to PHVS and KOD?
Nektar Therapeutics' ROE % Adjusted to Book Value of -14.65% can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good ROE % Adjusted to Book Value for a Biotechnology company?
A good ROE % Adjusted to Book Value depends on the Biotechnology industry context. However, ROE % Adjusted to Book Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high ROE % Adjusted to Book Value mean?
A high ROE % Adjusted to Book Value can signal that a stock is expensive relative to its fundamentals. Return on equity adjusted to book is the ratio of return on equity to price-book ratio. View historical data on Nektar Therapeutics and its competitors. Nektar Therapeutics's current ROE % Adjusted to Book Value is -14.65%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Nektar Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Nektar Therapeutics (NKTR) is currently considered Significantly Overvalued. The stock's GF Value™ is $6.01, compared to a current price of $65.14 — trading 983.9% above its estimated fair value. The current ROE % Adjusted to Book Value is -14.65%. Nektar Therapeutics' overall GF Score™ is 42/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is ROE % Adjusted to Book Value calculated?
ROE % Adjusted to Book Value is calculated from a company's financial statements. For Nektar Therapeutics (NKTR), the current ROE % Adjusted to Book Value is -14.65% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Nektar Therapeutics (NKTR) Overvalued in 2026?

Based on GuruFocus' analysis, Nektar Therapeutics stock appears to be overvalued. The current stock price of $65.14 is trading 983.9% above its estimated GF Value™ of $6.01. GuruFocus considers Nektar Therapeutics to be Significantly Overvalued.

Key valuation signals for NKTR:

  • ROE % Adjusted to Book Value: -14.65%
  • GF Value™: $6.01 vs. price of $65.14 (983.9% above fair value)
  • GF Score™: 42/100 with 5 warning signs

No single metric tells the full story. See the NKTR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Nektar Therapeutics Business Description

Other Exchanges 0UNL:UKITH0:Germany
Address 455 Mission Bay Boulevard South, San Francisco, CA, USA, 94158
Nektar Therapeutics is a clinical-stage, research-based biopharmaceutical company headquartered in San Francisco, California, and incorporated in Delaware, focused on discovering and developing medicines in the field of immunotherapy. The Company directs its efforts toward creating immunomodulatory agents that selectively induce, amplify, attenuate, or prevent immune responses to achieve desired therapeutic outcomes. Its pipeline of clinical-stage and preclinical-stage immunomodulatory agents targets the treatment of autoimmune diseases, including rezpegaldesleukin, NKTR-0165, NKTR-0166, and NKTR-422, as well as cancer, including NKTR-255.
42GF Score

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ROE % Adjusted to Book Value is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$65.14
Price
$6.01
GF Value