Alnylam Pharmaceuticals Inc at Piper Sandler Healthcare Conference Transcript

Nov 29, 2023 / 02:30PM GMT
Edward Andrew Tenthoff - Piper Sandler & Co., Research Division - MD & Senior Research Analyst

Good morning. My name is Ted Tenthoff. I'm a senior biotech analyst at Piper Sandler. And before I begin, I'm required to point out certain disclosures regarding the relationship between Piper and our next presenting company, Alnylam, which are posted at the back of the room and also at the registration desk. And that's a long time of disclosures. I remember doing the Alnylam IPO, it's one of the first ones that I did at Piper 20 years ago. So it really shows you the long relationship that we have with Alnylam.

As you know, Alnylam is a leading developer of RNA therapeutics with a growing commercial business and a rich pipeline of future therapies. After a roller coaster review, the FDA issued a CRL for ONPATTRO in hereditary and wild-type ATTR amyloidosis with cardiomyopathy, sending Alnylam shares lower. But I really want to own Alnylam right now for AMVUTTRA growth in the upcoming Phase III HELIOS-B data in early next year, which are positive, would expand the label and make up for the

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